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These are all the courses offered in the School of Biochemistry, Genetics & Microbiology
How to Understand a Syllabus
In order to understand the syllabus section that follows, consider the following example:
The title is Electromagnetism, Waves and Modern Physics
The code PHYS120 P2 W2 shows that the syllabus is in Physics (“PHYS”) and that it is at Level 1. The 2 & 0 have no special significance. P2 and W2 show that it is offered in semester 2 at Pietermaritzburg and Westville. Similarly W1 would show it is offered in semester 1 in Westville. Other codes are B if the module is offered in both semesters, C if it may be offered in either the first or second semester, Y if it is a year-long module, and V if it is offered in the
Winter vacation. Thus, for example, GEOL304 WV is a Westville module in Geology in 3rd year during the Winter vacation.
The notional study hours
(39L-9T-36P-0S-54H-15R-0F-0G-7A-13W-16C)
are interpreted as follows:
39L means 39 hours of lectures, i.e. 52 lectures of 45 minutes
9T means 9 hours of tutorials 36P means 36 hours of practicals
0S means 0 hours of seminars 54H means 54 hours of self-study
15R means 15 hours of revision 0F means 0 hours of field attachments
0G means 0 hours for problem based groups 7A means 7 hours of assessment (formal tests and exams)
13W means the module runs for 13 weeks 16C means the module is worth 16 credits.
The meanings of “prerequisite”, “corequisite” and “DP requirements” are explained in the definitions at the beginning of the handbook. It is assumed that no explanation is needed for “aims”, “content” etc.
Biochemistry
Offered in the School of Biochemistry, Genetics, Microbiology & Plant Pathology
Introductory Biochemistry and Microbiology
BIMI120 P2 W2 (36L-10T-36P-0S-55H-17R-0F-0G-6A-13W-16C)
Prerequisite: 40% in CHEM110.
Aim: To introduce students into the world of biochemistry and microbes.
Content: Major organic compounds of living organisms. Factors involved in biochemical reactions: thermodynamics, redox potential and enzymology; energy requirements for living organisms. Genes and their influence on the
organism. Discovery of micro-organisms. Definitions, scope, principles and concepts in Bacteriology, Mycology, Virology and Microbial Biotechnology. Microbiological methods: from aseptic techniques to microscopy. Microbial
growth. Role & applications of microorganisms in Agriculture, Industry and the Environment.
Practicals: Introduction to practical aspects of Biochemistry and Microbiology.
Assessment: Tests, reports and other class assignments (40%), 3 h exam (60%).
DP Requirement: Class mark of 40%, attendance at 80% of tutorials and practicals.
Offered in Semester 2.
Introduction to Biomolecules
BIOC201 P1 W1 (39L-10T-39P-0S-48H-18R-0F-0G-6A-13W-16C)
Prerequisite: BIMI120 or BIOL101, CHEM110, CHEM120.
Aim: To provide an insight into the molecular diversity in living systems.
Content: Hierarchy of chemical structures in prokaryotic and eukaryotic cells. Chemistry of carbohydrates, amino
acids, peptides and proteins. Introductory enzymology and kinetics. Structure and function of vitamins and cofactors.
Nucleic acid biochemistry and protein synthesis.
Practicals: Analyses of carbohydrates, amino acids, proteins and vitamins.
Assessment: Theory tests (25%), practical test and reports (25%) and 3 h exam (50%).
DP Requirement: Class mark of 40%, attendance at 80% of tutorials and practicals.
Offered in Semester 1. Credit may not be obtained for BIOC201 and BIOC203.
Bioenergetics and Integrated Metabolism
BIOC202 W2 (39L-10T-39P-0S-48H-18R-0F-0G-6A-13W-16C)
Prerequisite: BIMI120, BIOL101, CHEM110, CHEM120.
Aim: To introduce students to integrated biochemical pathways.
Content: The biosynthesis and oxidation of simple and complex lipids, lipid storage disorders. The metabolism of carbohydrates, amino acids, porphyrins, nucleotides and one-carbon fragments. Clinical correlations resulting from aberrations in individual metabolic pathways. Bioenergetics, regulation and control of metabolic pathways.
Practicals: Spetrophotometric techniques, electrophoresis and chromatography of serum and other metabolites.
Assessment: Theory test (25%), practical test and practical reports (25%) and 3 h exam (50%).
DP Requirement: Class mark of 40%, attendance at 80% of tutorials and practicals.
Offered in Semester 2. Credit may not be obtained for BIOC202 and BIOC203.
Biochemical Aspects of Microbial Pathogenesis
BIOC204 P2 (36L-9T-37P-0S-45H-24R-3F-0G-6A-13W-16C)
Prerequisite: BIOC201.
Aim: To provide insight into the biochemical mechanisms of microbial pathogenicity, cell biological processes & cell-toxin interactions at the molecular level as well as the importance of health & veterinary policies and health regulations.
Content: Molecular aspects of viral and microbial components in host colonization and pathogenicity & host defence; proteins & toxins produced during invasion and infection, or during growth in food and water; mode of action at the cellular level, symptoms of infection; food and water testing.
Practicals: Culture & identification of human, food & water pathogens, antibiotic sensitivity testing, field trip, written assignment & presentation.
Assessment: Practical reports or assignments (15%), tests (35%), 3 h exam (50%).
DP Requirement: Class mark of 40%, attendance at 80% of tutorials and practicals.
Offered in Semester 2.
Signal Transduction and Metabolism
BIOC212 P2 (36L-22T-22P-0S-56H-18R-0F-0G-6A-13W-16C)
Prerequisite: 40% in (BIMI120 or BIOL101), CHEM110, 120.
Aim: To introduce the fundamentals of cell biology.
Content: Classification and function of lipids; function and properties of biological membranes; subcellular organelles. Bioenergetics of metabolism. Carbohydrate, lipid and amino acid metabolism; photosynthesis and nitrogen metabolism. Integration and regulation of metabolic pathways in animals, humans, plants, and microbes.
Practicals: Extraction & analyses of cell components & diagnostic procedures. Video illustration of properties & role of lipids in signal transduction.
Assessment: Continuous assessment, 6h theory & prac tests.
DP Requirement: Class mark of 40%, attendance at 80% of tutorials and practicals.
Offered in Semester 2.
Protein Structure & Function
BIOC304 P2 (14L-7T-12P-0S-32H-12R-0F-0G-3A-13W-8C)
Prerequisite: BIOC201, 212, CHEM220.
Aim: To provide insight into the three levels of protein structure and the relationship between the structure and function (and evolution) of proteins.
Content: Concepts and methods in the determination of primary, secondary and tertiary structures of proteins; methods for the representation of the 3-D structure of proteins and the families of proteins which have thus been identified; mapping of enzyme active sites; enzyme reaction mechanisms.
Practicals: Computer-based exercises using animations & other tools to study protein structure & function.
Assessment: Continuous assessment: assignments, 3 h of quizzes and class tests (no exams).
DP Requirement: Class mark of 40%, attendance at 80% of tutorials and practicals.
Offered in Semester 2.
RNA Chemistry and Gene Expression
BIOC307 W1 (30L-7T-36P-0S-57H-25R-0F-0G-5A-13W-16C)
Prerequisite: BIOC201, 202, RDNA202, 40% in CHEM220.
Aim: To introduce students to more advanced aspects of gene expression in prokaryotes and eukaryotes.
Content: Structure and chemistry of RNA. RNA-modifying enzymes. Transcription in prokaryotes and eukaryotes. Control of transcription. Inhibitors, enhancers, promoters and transcription factors. Post-transcriptional modifications of RNA. Aminoacyl tRNA synthetases, codon-anticodon interactions, ribosome structure/morphology. Polypeptide synthesis, translational accuracy, inhibitors and control of translation. Post-translational modifications and protein degradation.
Practicals: Methods of RNA isolation, characterization and quantification.
Assessment: Theory test (25%), practical reports and test (25%), 3 h exam (50%).
DP Requirement: Class mark of 40%, attendance at 80% of tutorials and practicals.
Offered in Semester 1.
Regulation of Metabolism
BIOC310 P2 (14L-20T-0P-0S-31H-12R-0F-0G-3A-13W-8C)
Prerequisite: BIOC201, 212.
Aim: To provide insight into how metabolism is regulated, and can be manipulated, in cells and whole organisms. Content: The integration and regulation of metabolism in animals, humans, plants and microbes under normal, and stressful conditions such as exercise, disease (e.g. heart disease and diabetes), and toxicity (e.g. microbial toxins and drugs). Application of metabolic control analysis to metabolic regulation and the manipulation of genes and metabolic pathways in biotechnology and in the treatment of disease.
Assessment: 1 h test, assignments (50%), 2 h exam (50%).
DP Requirement: Class mark of 40%, attendance at 80% of tutorials and practicals.
Offered in Semester 2.
Biochemical Methods
BIOC311 P1 (27L-10T-22P-0S-71H-25R-0F-0G-5A-13W-16C)
Prerequisite: BIOC201, 212, PHYS131.
Aim: To introduce techniques for protein, DNA, lipid and carbohydrate identification, isolation and analysis for biochemical, biological, medical, agricultural, and food sciences.
Content: Identification, extraction, separation and analysis of proteins, DNA, lipids and carbohydrates; centrifugation, precipitation, chromatography, electrophoresis, laboratory safety, cell culture, accessing the scientific literature.
Practicals: Techniques for protein, DNA, lipid and carbohydrate identification, isolation and analysis
Assessment: 2 h class tests, assignments (33%), 3 h exam (67%).
DP Requirement: Class mark of 40%, attendance at 80% of tutorials and practicals.
Offered in Semester 1.
DNA Chemistry
BIOC315 P1 W1 (30L-10T-30P-0S-60H-25R-0F-0G-5A-13W-16C)
Prerequisite: BIOC201, (BIOC202 or 212), RDNA202, 40% in CHEM220.
Aim: To provide a detailed account of the chemistry and biochemistry of DNA and aspects of its manipulation.
Content: Molecular structure, enzymology, synthesis and repair of nucleic acids; advanced recombinant nucleic acid methodology, sequencing and analysis.
Practicals: DNA isolation, characterisation and manipulation.
Assessment: Continuous assessment (50%), 3 h exam (50%).
DP Requirement: Class mark of 40%, attendance at 80% of tutorials and practicals.
Offered in Semester 1.
Immuno- and Protein Chemistry
BIOC316 P2 W2 (30L-8T-30P-0S-62H-25R-0F-0G-5A-13W-16C)
Prerequisite: BIOC201, (BIOC202 or 212), CHEM220, RDNA202.
Aim: To introduce a biochemical view of immunology and advanced aspects of protein conformation as well as to develop skills in the concomitant laboratory techniques.
Content: Innate and acquired immunity, biochemistry of humoral and cell-mediated immune responses, antibody-antigen interactions, immune cell receptors, cytokines; protein conformation and folding; peptide synthesis.
Practicals: Physico-chemical analysis of proteins and immunochemical techniques.
Assessment: Continuous assessment (50%), 3 h exam (50%).
DP Requirement: Class mark of 40%, attendance at 80% of tutorials and practicals.
Offered in Semester 2.
Genetics
Offered in the School of Biochemistry, Genetics, Microbiology & Plant Pathology
Introductory Genetics
GENE213 P1 (36L-36T-0P-0S-53H-28R-0F-0G-7A-13W-16C)
Prerequisite: BIOL101, 102, MATH133.
Aim: To attain an understanding of basic inheritance patterns and to solve relevant problems.
Content: The rules of inheritance in cells, individuals, and populations and the molecular mechanisms by which genes control the growth, development and appearance of an organism. Provides grounding in the areas of Mendelian genetics, molecular genetics, cytogenetics and population genetics linking basic concepts to applied examples in agriculture, medicine, breeding and other fields of interest.
Practicals: Tutorials. Problem solving exercises.
Assessment: 2 h theory and 2 h tutorials tests (50%), 3 h exam (50%).
DP Requirement: 40% Class mark. 80% attendance at tutorials and 100% at tests. Completion and submission of all
assignments on time.
Offered in Semester 1.
Further Introduction to Genetics
GENE214 P2 (36L-18T-18P-0S-53H-28R-0F-0G-7A-13W-16C)
Prerequisite: GENE213.
Aim: To attain an insight into the genetics of eukaryotes including structure and function of eukaryotic genomes in cells, individuals and populations, and the evolutionary processes that modify genomes.
Content: Theory of eukaryotic DNA and structure organization, gene expression and gene control. Methods of cytogenetics evolution. Chromosome number (polyploidy and aneuploidy) and structure (deletion, duplication, inversion and translocation) variation. Asexual reproduction.
Practicals: Preparation of slides of mitosis and meiosis and analysis of chromosome behaviour and karyotype analysis. Analysis of Eukaryotic molecular and cellular systems. Problem solving exercises.
Assessment: 2 h theory & 2 h tutorials tests and practical tests (50%); 3 h exam (50%).
DP Requirement: 40% Class mark. 80% attendance at practicals and 100% at tests. Completion and submission of all assignments on time.
Offered in Semester 2.
Molecular Population Genetics & Diagnostics
GENE319 P1 (18L-4T-18P-0S-24H-10R-0F-0G-6A-13W-8C)
Prerequisite: GENE213.
Aim: To attain an understanding of the principles of molecular diversity in individuals, populations and species, and gain insight into genotyping and molecular diagnostic techniques and their application.
Content: Principles underlying the analysis of genes and genomes. Comparison of techniques used in genotyping and forensics, e.g. allozymes, RFLP, AFLP, microsatellites. Development of molecular diagnostics.
Practicals: Hands-on experience of molecular techniques and data analysis.
Assessment: 2 h theory & 2 h practical tests, practical reports (33%), 2 h exam (67%).
DP Requirement: 40% in coursework. 80% attendance at practicals and 100% at tests. Completion and submission of all assignments on time.
Offered in Semester 1.
Bioinformatics and Molecular Phylogenetics
GENE323 P2 (27L-10T-20P-0S-73H-25R-0F-0G-5A-13W-16C)
Prerequisite: GENE213.
Aim: To attain an understanding of the basic theory of molecular evolutionary genetics and bioinformatics and gain practical experience of DNA and protein sequence analysis including the understanding of the basic theory of
molecular phylogenetics.
Content: Modes of evolutionary change in DNA and protein sequences, sequence alignment algorithms, structure function prediction, and organization and use of public domain sequence databases. Including the principles underlying the phylogenetic analysis of DNA and protein sequences.
Practicals: Hands-on experience with the retrieval and manipulation of data from online databases.
Assessment: 2 h theory Test and Prac. Reports (33%), 3 h exam (67%).
DP Requirement: 40% Class mark. 80% attendance at tutorials and practicals, 100% attendance at tests.
Offered in Semester 2.
Foundational Eukaryotic Genetics
GENE329 P1 (27L-10T-27P-0S-70H-21R-0F-0G-5A-13W-16C)
Prerequisite: GENE213.
Aim: To attain an in depth knowledge of the genetics of Eukaryotes including structure and function of eukaryotic genomes in cells, individuals and populations. Insight, skills and experience in eukaryotic recombinant DNA technology and in-vitro cell manipulation.
Content: Theory of eukaryotic DNA and structure organization, gene expression and gene control. Including the theory of cloning, manipulation and analysis of DNA and protein sequences from a eukaryotic perspective. This includes providing a working knowledge of enzymology and recombinant DNA technology used in genetic engineering of eukaryotes.
Practicals: Analysis of eukaryotic molecular and cellular systems.
Assessment: 2 h theory test & prac reports (33%), 3 h exam (67%).
DP Requirement: 40% Class mark. 80% attendance at tutorials, practicals and 100% at tests. Completion and
submission of all assignments on time.
Offered in Semester 1.
Introduction to Quantitative Genetics
GENE332 P1 (18L-15T-0P-0S-26H-15R-0F-0G-6A-13W-8C)
Prerequisite: GENE213.
Corequisite: BMET210.
Aim: To attain insight into the principles of Mendelian inheritance when extended to the properties of populations and to the simultaneous segregation of genes at many loci.
Content: Components of genetic variation, resemblance between relatives, heritability, selection, genotype- environment interaction and threshold traits.
Practicals: Tutorials. Problem solving exercises.
Assessment: 2 h theory & 2 h tutorials tests (33%), 2 h exam (67%).
DP Requirement: 40% Class mark. 80% attendance at tutorials and 100% at tests. Completion and submission of all assignments on time.
Offered in Semester 1.
Eukaryotic Genome Evolution
GENE342 P2 (18L-18T-0P-0S-21H-17R-0F-0G-6A-13W-8C)
Prerequisite: GENE213.
Aim: To attain an understanding of the principles underlying gene and karyotype change and the consequences thereof on speciation and genetic diversity.
Content: Different mechanisms of gene and karyotype change; gene mutations, recombination and chromosome mutations. Effects of changes of gene frequencies and changes of recombinational potential on speciation. Genetic recombination control systems in plants and animals.
Practicals: Tutorials. Analysis of evolutionary change and problem solving debates.
Assessment: 2 h theory, 2 h tutorial & oral tests (33%), 2 h exam (67%).
DP Requirement: 40% Class mark. 80% attendance at tutorials and 100% at tests. Completion and submission of all assignments on time.
Offered in Semester 2.
Animal Genetics
GENE350 P2
Prerequisite: GENE213.
(36L-36T-0P-34S-17H-30R-0F-0G-7A-13W-16C)
Aim: To attain insight into how genetic principles may be used to assess and predict, and thereby improve the genetic merit of animal populations.
Content: Aspects of cytogenetics, molecular genetics, population genetics, conservation genetics, quantitative genetics and biotechnology, with special reference to their application and use in animal populations.
Practicals: Tutorials. Problem solving exercises and field trips.
Assessment: 2 h theory & 2 h tutorial tests, 1 seminar (50%); 3 h exam (50%).
DP Requirement: 40% Class mark. 80% attendance at tutorials and practicals, 100% attendance at tests. Completion and submission of all assignments on time.
Offered in Semester 2.
Human Genetics
GENE360 P2 (18L-0T-18P-0S-28H-10R-0F-0G-6A-13W-8C)
Prerequisite: GENE213.
Aim: To attain an understanding of the diverse nature of human genetic studies, apply principles to the solution of genetic problems through cytomolecular and quantitative assessment of data.
Content: The organisation of the human genome and mapping; somatic cell genetics; identifying the genetic basis of disease; genetic screening and prenatal diagnosis; treatment of genetic disease; genetic basis of cancer and the immune system; mitochondrial pathology and the human genome project.
Practicals: Human cytogenetics preparations, tutorials and problem solving debates.
Assessment: 2 h theory & 2 h prac tests (33%), 2 h exam (67%).
DP Requirement: 40% Class mark. 80% attendance at practicals and 100% at tests. Completion and submission of all assignments on time.
Offered in Semester 2.
Research Project in Genetics
GENE701 PY (0L-20T-300P-1S-158H-0R-0F-0G-1A-26W-48C)
Prerequisite: 128C in Genetics, Biochemistry and/or Molecular Biology disciplines at Level 3, or modules providing adequate background approved by the academic coordinator.
Aim: To provide insight to the principles of conducting research through laboratory based and/or computer based research and developing the skills to analyze, interpret and present results.
Content: Research project which falls within the thrust of the school’s research area. This includes a relevant literature survey and the execution of research.
Practicals: Design and execution of a research project.
Assessment: Written & 1 h oral presentations, 30 minutes oral exam.
DP Requirement: 50% Class mark. 80% attendance at lectures, tutorials, and practicals, 100% attendance at tests.
Completion and submission of all assignments on time.
Year-long Module.
Advanced Techniques in Genetics
GENE707 P1 (6L-40T-100P-0S-163H-10R-0F-0G-1A-13W-32C)
Prerequisite: 128C at Level 3 taken from Genetics or modules providing adequate background approved by the Academic Coordinator.
Aim: To introduce students to laboratory /computer research environments.
Content: Recombinant DNA and protein genetics, advanced DNA diagnostic and analysis techniques including forensic techniques.
Practicals: Hands-on laboratory-based and computer-based advanced techniques in genetics.
Assessment: Written & oral presentations (100%).
DP Requirement: 50% Class mark. 80% attendance at lectures, tutorials, and practicals, 100% attendance at tests.
Completion and submission of all assignments on time.
Offered in Semester 1.
Seminars/Discussions in Genetics
GENE709 PC (0L-0T-22P-0S-56H-0R-0F-0G-2A-13W-8C)
Prerequisite: 128C at Level 3 taken from Genetics or modules providing adequate background approved by the Academic Coordinator.
Aim: To develop skills to access, collect and crystallize scientific information on recent topics in genetics and through discussions, verbal and written presentations.
Content: Written and oral overviews of selected topics in Genetics are prepared and presented, including a number of article discussions.
Assessment: 2 h oral presentations, report/seminar (100%).
DP Requirement: 50% Class mark, 80% attendance at lectures and practicals. Completion and submission at all assignments on time.
Offered in either Semester 1 or 2.
Advanced Topics in Genetics 1
GENE711 P2 (44L-0T-0P-4S-109H-0R-0F-0G-3A-13W-16C)
Prerequisite: 128C at Level 3 taken from Genetics or modules providing adequate background approved by the Academic Coordinator.
Aim: To introduce the latest developments in genetics.
Content: Selected advanced topics in Genetics.
Assessment: 1 or more oral presentations, report/seminar or 3 h theory exam (100%).
DP Requirement: 50% Class mark. 80% attendance at lectures. Completion and submission of all assignments on time.
Offered in Semester 2.
Research Techniques
GENE712 P2 (9L-6T-12P-0S-50H-0R-0F-0G-3A-13W-8C)
Prerequisite: 128C at Level 3 taken from Genetics or modules providing adequate background approved by the Academic Coordinator.
Aim: To introduce research planning, data analysis and research documentation.
Content: Literature review, project planning, writing and presentation skills, including posters.
Practicals: Tutorials.
Assessment: 1 or more written and/or oral examinations (100%).
DP Requirement: 50% Class mark. 80% attendance at lectures, tutorials and practicals. Completion and submission of all assignments on time.
Offered in Semester 2.
Laboratory Practice and Management
GENE717 P1 (9L-6T-12P-0S-50H-0R-0F-0G-3A-13W-8C)
Prerequisite: 128C at Level 3 taken from Genetics or modules providing adequate background approved by the Academic Coordinator.
Aim: To introduce the principles related to the use of genetics laboratory equipment and management.
Content: Selected topics on the use of standard and sophisticated equipment used in the laboratories of the discipline of genetics, management practices, such as budgeting, database management, human relationships and ethics.
Practicals: Hands-on experience with the use of genetics laboratory equipment and laboratory management.
Assessment: 1 or more written and/or oral examinations (100%).
DP Requirement: 50% Class mark. 80% attendance at lectures, tutorials and practicals. Completion and submission of all assignments on time.
Offered in Semester 1. Subminimum to pass: 50% in presentation and 2 assignments.
Advanced Topics in Genetics 2
GENE722 PC (0L-20T-0P-4S-55H-0R-0F-0G-1A-13W-8C)
Prerequisite: 128C at Level 3 taken from Genetics or modules providing adequate background approved by the Academic Coordinator.
Aim: To introduce the latest developments in genetics.
Content: Selected advanced topics from the discipline of genetics.
Assessment: 1 or more written and/or oral examinations (100%).
DP Requirement: 50% Class mark,. 80% attendance at lectures. Completion and submission of all assignments on
time.
Offered in either Semester 1 or 2.
Quantitative Genetics
GENE732 PC (18L-15T-0P-0S-27H-15R-0F-0G-5A-13W-8C)
Prerequisite: GENE332 or modules which in the opinion of the Academic Coordinator (and with approval of the Dean) have provided the candidate with adequate background.
Aim: To attain insight into the principles of Mendelian inheritance when extended to the properties of populations and to the simultaneous segregation of genes at many loci.
Content: Artificial selection, genotype-environment interaction, genetic correlations, inbreeding and crossbreeding, evolutionary quantitative genetics, mapping of QTL's and aspects of experimental design.
Practicals: Tutorials. Problem solving exercises.
Assessment: 2 h theory test (33%), 3 h exam (67%).
DP Requirement: 50% Class mark, 80% attendance at lectures, tutorials and tests. Completion and submission of all
assignments on time.
Offered in either Semester 1 or 2.
Microbiology
Offered in the School of Biochemistry, Genetics, Microbiology & Plant Pathology
Agricultural Microbiology
MICR212 P2 (18L-6T-18P-0S-23H-12R-0F-0G-3A-6W-8C)
Prerequisite: BIOL101 or BIMI120, CHEM110.
Aim: To provide key concepts and application in the area of agricultural microbiology.
Content: Introduction to the morphology, physiology and classification of microorganisms. Parasitism and symbiosis; soil-rumen-dairy-water- and industrial-microbiology. Role of microorganisms in legumes, the rumen and in cycling of the elements N, C, S and P. Microbiological aspects of composting and silage making; role of microbial associations in bioremediation of polluted agricultural soils; microbiological treatment of contaminated water. Selected topics in agricultural industrial microbiology.
Practicals: Laboratory exercises in selected topics from the above.
Assessment: Tests, assignments, prac reports (33%), 1.5 h exam (67%).
DP Requirement: 40% Class mark, 80% attendance at practicals.
Offered in Semester 2.
Bacteriology
MICR213 P1 W1 (36L-6T-36P-0S-53H-24R-0F-0G-5A-13W-16C)
Prerequisite: CHEM110, BIMI120 or BIOL101.
Aim: To provide a strong foundation in the field of bacteriology.
Content: Morphology and ultrastructure of bacteria; relationship of cellular structure to function. Physiological-
nutritional groups among the bacteria. Cultivation of bacteria and elementary aspects of control of microorganisms.
Introduction to microbial ecology and habitat specific species. Basic aspects of environmental microbiology. Metabolic pathways of industrial importance. Introduction to classification of bacteria. Basic bacteriological aspects of immunology.
Practicals: Handling bacteria; aseptic technique; cultural practices; staining procedures; microscopy.
Assessment: Tests, assignments, prac reports (33%), 3 h exam (67%).
DP Requirement: 40% Class mark, 80% attendance at practicals.
Offered in Semester 1.
Introductory Food Microbiology
MICR214 P2 (18L-6T-18P-0S-23H-12R-0F-0G-3A-13W-8C)
Prerequisite: BIOL101 or BIMI120, CHEM110.
Aim: To provide concepts and applications in food microbiology.
Content: The morphology, physiology and classification of microorganisms. Aspects of food, diary and water microbiology, including food safety and preservation; use of microorganisms in the production of selected fermented food and dairy products, and the importance of safe sources of water. Methods of preventing post harvest food spoilage and food poisoning are discussed. Principles of food safety. Nutritional enhancement of foodstuffs by microorganisms. Selected topics in food-orientated industrial microbiology applications.
Practicals: Laboratory exercises in selected topics.
Assessment: Tests, assignments, prac reports (33%), 1.5 h exam (67%).
DP Requirement: 40% Class mark, 80% attendance at practicals.
Offered in Semester 2.
Mycology
MICR216 W1 (39L-9T-39P-0S-54H-6R-6F-0G-7A-13W-16C)
Prerequisite: CHEM110, BIMI120 or BIOL101.
Aim: To introduce students to fungi and their importance.
Content: General characteristics of fungi. Principles and practice of fungal taxonomy. Importance of fungi. Fungal diseases of plants and humans. Symbiotic relationships - mycorrhizae and lichens.
Practicals: Microscopy. Fungal succession. Isolation, purification and identification of fungal cultures.
Assessment: 2 theory tests (25%), 2 practical tests, laboratory and practical reports (25%), 3 h exam (50%).
DP Requirement: 40% Class mark, 80% attendance at practicals.
Offered in Semester 2.
Microbial Metabolism and Ecology
MICR218 W2 (39L-9T-39P-0S-61H-6R-0F-0G-6A-13W-16C)
Prerequisite: CHEM110, BIMI120 or BIOL101.
Aim: To introduce the fundamental aspects of microbial ecology & metabolism.
Content: Energy needs for microbial cells, energy yielding sources for micro-oganisms. Energy utilization for biosynthetic processes. Bacterial enzymes & their regulation. Biogeochemical cycling of elements. Microbe & microbe-host interactions. Micro-organism in their natural habitat. Techniques for the study of microbial ecosystems.
Practicals: Winogradski column. Sauerkraut fermentation. Bacterial associations. Viscometric determination of enzyme activity. Protein determination; the Folin-Lowry method. Manometry. Determination of cellulase, dehydrogenase & protease activities.
Assessment: Theory tests (25%), Prac tests, lab & report writing (25%), 3 h exam (50%).
DP Requirement: 40% Class mark, 80% attendance at practicals.
Offered in Semester 1.
Environmental Biotechnology
MICR303 W2 (39L-9T-39P-0S-55H-6R-6F-0G-6A-13W-16C)
Prerequisite: MICR213 and MICR218.
Aim: To introduce students to the fundamental aspects of environmental biotechnology.
Content: The need for the protection of the environment. Sources and consequences of pollution. Strategies for the treatment of solid and liquid wastes. Application of biosensors for environmental biotechnology. Bioremediation of xenobiotic and inorganic pollutants: Approaches and evaluation.
Practicals: Determination of the sanitary quality of water from various sources. Bioremediation. Use of biosensors for detecting pollutants. Field trips.
Assessment: Theory tests and assignments (25%), Practical tests and laboratory and report writing performance
(25%), 3 h exam (50%).
DP Requirement: 40% Class mark, 80% attendance at practicals.
Offered in Semester 2.
Microbial Processing
MICR304 P2 W2 (29L-7T-42P-0S-53H-24R-0F-0G-5A-13W-16C)
Prerequisite: MICR213.
Aim: To introduce the key concepts & applications in microbial bioprocessing.
Content: Range and scope of microbial bioprocessing. Growth of microbes in a controlled environment; including nutrient requirements, kinetics, environmental parameters, and monitoring. Batch & continuous bioprocesses. Aspects of upstream and downstream processing. Examples of major fermentation processes. Current trends and applications in industrial biotechnology. Regulatory, safety (Hazard Analysis Critical Control Point) and socio-economic consideration of Biotechnology.
Practicals: Related laboratory work. Field trips to facilities employing microbiological processes.
Assessment: Assessment: Theory tests and assignments, practical tests and laboratory reports (40%); 3 h exam (60%).
DP Requirement: 40% in Class Mark, 80% attendance at practicals.
Offered in Semester 2.
Introduction to Viruses
MICR305 P1 W1 (29L-7T-42P-0S-53H-24R-0F-0G-5A-13W-16C)
Prerequisite: RDNA202.
Aim: This module introduces viruses, the diseases they cause, control and applications.
Content: General characteristics of viruses, viroids, virusoids, mycoplasmas and prions. Taxonomy, identification, transmission, epidemiology, identification, characterization, control and applications.
Practicals: An introduction to the techniques used to detect and characterize plant and animal viruses.
Assessment: Theory tests and assignments, practical tests and laboratory reports (40%), 3 h exam (60%).
DP Requirement: 40% Class mark, 80% attendance at practicals.
Offered in Semester 1.
Soil Microbiology
MICR310 P1 (29L-7T-48P-0S-47H-24R-0F-0G-5A-13W-16C)
Prerequisite: MICR212 or MICR213.
Aim: To provide a knowledge of the role of micro-organisms in agricultural and other soils.
Content: Microbiota found in soil; range and scope. Physical and chemical aspects of soil structure and its influence on micro-organisms. Environmental variables influencing microbial activity. Introduction to microbial interactions, development of microbial communities and ecosystems. Introduction to biochemical cycling. Microbial participation in C, N, S and P cycles. Introduction to environmental biotechnology.
Practicals: An introduction to techniques used in microbial ecology. Excursions to facilities employing environmental biotechnological methods.
Assessment: Tests (17%), prac reports, essays and assignments (17%), 3 h exam (66%).
DP Requirement: 40% Class mark, 80% attendance at practicals.
Offered in Semester 1.
Advanced Bacteriology
MICR311 W1 (39L-9T-39P-0S-61H-6R-0F-0G-6A-13W-16C)
Prerequisite: MICR213, 218.
Aim: To introduce students to advanced topics in bacteriology.
Content: Bacterial taxonomy and the principles and practice of bacterial classification. Study of bacterial prokaryotic diversity and techniques involved in elucidating their diversity. Detailed study of prokaryotic cell structure and function.
Archeabacteria.
Practicals: Identification of unknown bacterial cultures by use of dichomatous keys and API kits. Antibiotic sensitivity testing. Electron microscopy.
Assessment: Theory tests and assignments (25%), Practical tests and laboratory and report writing performance
(25%), 3 h exam (50%).
DP Requirement: 40% Class mark, 80% attendance at practicals.
Offered in Semester 1.
Advanced Mycology
MICR313 W2 (39L-9T-39P-0S-53H-13R-0F-0G-7A-13W-16C)
Prerequisite: MICR216.
Aim: To introduce advanced topics in mycology.
Content: Fungal taxonomy & classification. Physiology & biochemistry of fungal cells. Environmental factors in growth, & reproduction. Fungal genetics: mechanisms of variability, gene-for-gene hypothesis, breeding for resistance,
pathological alterations. Applied mycology: field fungi, storage fungi & crops of economic importance, mycotoxins, fungal diseases.
Practicals: Colonisation of buried cellophane, environmental factors in growth of F. oxysporum; Mycostasis using T. roseum; Isolation, identification of fungal cultures from seeds; Measurement of Amylase & Invertase in leaf tissues.
Assessment: 2 theory tests & assignments (25%), 2 practical tests, projects & prac reports (25%), 3 h exam (50%).
DP Requirement: 40% Class mark, 80% attendance at practicals.
Offered in Semester 1.
Role of Microorganisms in the Soil
MICR316 P1 (18L-0T-24P-0S-23H-12R-0F-0G-3A-13W-8C)
Prerequisite: MICR213 or PPTH214.
Aim: To provide a knowledge of the role of micro-organisms in agricultural soils.
Content: Microbiota found in soil; range and scope. Physical and chemical aspects of soil structure and its influence on micro-organisms. Environmental variables influencing microbial activity. Introduction to microbial interactions, development of microbial communities and ecosystems. Introduction to biochemical cycling. Microbial participation in C, N, S and P cycles.
Practicals: Mini-research project and excursions to facilities employing environmental biotechnological methods.
Assessment: Tests, assignments, prac reports (33%), 1.5 h exam (67%).
DP Requirement: 40% Class mark, 80% attendance at practicals.
Offered in Semester 1. Students may not obtain credit for MICR310 and MICR316.
Advanced Microbial Metabolism & Ecophysiology
MICR320 P1 (29L-7T-40P-0S-55H-24R-0F-0G-5A-13W-16C)
Prerequisite: MICR213; BIOC201 or CHEM220.
Aim: To study microbial physiology and metabolism in natural ecosystems and industrial environments.
Content: Review of microbial metabolism and energy generation under aerobic and anaerobic conditions. Energy sources of chemolithotrophs, photoautotrophs and chemo-organotrophs. Metabolic regulatory systems in bacteria.
Biotechnological aspects of process control. Environmental impacts of microbial activity. Metabolic interactions in microbial populations.
Practicals: Experiments on microbial e-donors, e-acceptors and redox potential. Laboratory-scale industrial
microbiology processes. Excursions.
Assessment: 2 tests (17%), 3 h exam (66%), prac reports, essays & reports on excursions (17%).
DP Requirement: Class mark of 40%, attendance at 80% of tutorials and practicals.
Offered in Semester 1.
Research Project
MICR710 PY WY (0L-45T-200P-30S-205H-0R-0F-0G-0A-26W-48C)
Aim: To provide a grounding in research techniques & procedures in Microbiology.
Content: Students have an opportunity to obtain some degree of specialization in: Agricultural Biotechnology, Medical Biotechnology or Industrial and Environmental Microbiology & Biotechnology. In addition to the above, seminars and a research proposal, relevant to the Research Project are presented to the Staff and Students. The findings of the Research Project are submitted in the form of a bound mini-dissertation and also presented at a scientific forum.
Assessment: Project Report (70%), Literature Review, proposal presentation and Research paper (20%),
Conference presentation (10%).
DP Requirement: Not applicable.
Year-long Module.
Bacteriology
MICR711 W1 (24L-24T-0P-10S-66H-30R-0F-0G-6A-13W-16C)
Aim: To train students to critically evaluate recent peer-reviewed publications in Bacteriology.
Content: Topics pertinent to the ever expanding field of Bacteriology.
Assessment: Test (25%), Performance in Tutorials (15%), Seminars (10%), 3 h exam (50%).
DP Requirement: Class mark of 40%, attendance at 80% of tutorials.
Offered in Semester 1.
Mycology
MICR712 W1 (24L-24T-0P-10S-66H-30R-0F-0G-6A-13W-16C)
Aim: To train students to critically evaluate recent peer-reviewed publications in Mycology.
Content: Topics pertinent to latest developments in Mycology.
Assessment: Test (25%), Performance in Tutorials (15%), Seminars (10%), 3 h exam (50%).
DP Requirement: Class mark of 40%, attendance at 80% of tutorials.
Offered in Semester 1.
Molecular Genetics
MICR713 W2 (24L-24T-0P-10S-66H-30R-0F-0G-6A-13W-16C)
Aim: To train students to critically evaluate recent peer-reviewed publications in Molecular Genetics.
Content: Coverage of current publications in molecular genetics.
Assessment: Test (25%), Performance in Tutorials (15%), Seminars (10%), 3 h exam (50%).
DP Requirement: Class mark of 40%, attendance at 80% of tutorials.
Offered in Semester 2.
Industrial Bioprocessing Technology Project
MICR715 PY (0L-0T-300P-90S-90H-0R-0F-0G-0A-26W-48C)
Aim: To introduce students to the process of applied biotechnological research and to provide a sound training in
relevant research techniques/procedures.
Content: Writing literature reviews; research project design and implementation; data generation and analysis. Thesis
writing; research paper writing; oral presentation of research results.
Practicals: Research project.
Assessment: All work is conducted under supervision & will be assessed by the supervisor & an examiner external to
the University. Thesis (65%), research paper (10%), oral presentations (10%), literature review (15%).
DP Requirement: Not applicable.
Year-long Module.
Applied Environmental Microbiology
MICR716 P2 (0L-36T-0P-0S-100H-21R-0F-0G-3A-13W-16C)
Aim: To provide a sound training in environmental microbiology and microbial ecology.
Content: Microbial responses in healthy and polluted aquatic, terrestrial and atmospheric environments. Role of
microorganisms in biodeterioration and biodegradation processes (timber, fuels, lubricants, foodstuffs etc.), metal corrosion; defacing of man-made structures; microbiological mining; treatment of acidic mine wastewaters; removal of
toxic heavy metals from effluents and natural water sources.
Assessment: Performance in tests, tutorials, assignments & presentations (33%), 3 h exam (67%).
DP Requirement: Class mark of 40%, attendance at 80% of tutorials.
Offered in Semester 2.
Advanced Microbiology Topics
MICR717 P1 (0L-20T-0P-20S-90H-0R-30F-0G-0A-13W-16C)
Aim: To introduce students to a range of advanced topics in Microbiology.
Content: Topics pertinent to the ever expanding field of Microbiology.
Practicals: Field trips and industrial excursions.
Assessment: Assignments (100%).
DP Requirement: 80% attendance at tutorials & field trips.
Offered in Semester 1.
Environmental Microbiology
MICR718 P1 (0L-36T-0P-0S-100H-21R-0F-0G-3A-13W-16C)
Aim: To provide a sound training in environmental microbiology and waste technology at a relatively advanced level.
To expose students to microbiological sampling and analytical techniques used in this field.
Content: Role of micro-organisms in bioremediation processes: microorganism-microorganism, microorganism-environmental variable and environmental variable-environmental variable interaction underpinning selected environmental biotechnologies. Landfill microbiology, solid waste treatment, composting, land reclamation, industrial wastewater treatment, soil bioremediation, gas biofiltration.
Assessment: Performance in tests, tutorials, assignments & presentations (33%), 3 h exam (67%).
DP Requirement: Class mark of 40%, attendance at 80% of tutorials.
Offered in Semester 1.
Recombinant DNA Technology
Offered in the School of Biochemistry, Genetics, Microbiology & Plant Pathology
Molecular DNA Technology
RDNA202 P2 W2 (39L-10T-39P-0S-60H-7R-0F-0G-5A-13W-16C)
Prerequisite: BIOL101 or BIMI120; CHEM110, 120.
Aim: To provide a strong foundation in bacterial and viral molecular biology and recombinant DNA technology.
Content: Organisation of bacterial & viral genomes. DNA replication. Regulation of gene expression. Plasmid biology.
Transposons and mobile elements. DNA repair & recombination. Theory of cloning, manipulation & analysis of genes and the expression of their protein products. A working knowledge of genetic engineering.
Practicals: Hands on experience in screening for bacterial mutants, detection of antibiotic resistance, conjugation and transduction and bacteriophage cultivation. Hands on experience with basic recombinant DNA technology techniques.
Assessment: Theory tests, reports & other class assignments (50%), 3 h exam (50%).
DP Requirement: Class mark of 40%, attendance at 80% of tutorials and practicals.
Offered in Semester 2.
Science Education
Offered in the School of Biochemistry, Genetics, Microbiology & Plant Pathology
Understanding in Science & Mathematics
SCED701 P1 (0L-12T-0P-0S-68H-0R-0F-0G-0A-13W-8C)
Prerequisite: A Bachelors degree in science/mathematics, or any qualification approved by Senate.
Aim: To give students insight into current theories on how people learn and understand science and mathematics, and some methods for investigating student understanding and difficulties.
Content: The nature of understanding. Learning theories of Piaget, Ausubel, Vygotsky and constructivism, and their application to learning, teaching and assessment. Research methods for identifying conceptual and reasoning difficulties, especially in mathematics, physics, chemistry, biology, genetics, biochemistry and microbiology.
Assessment: Assignments (100%).
DP Requirement: Not applicable.
Offered in Semester 1.
Biotechnology
MICR719 W2 (24L-24T-0P-10S-68H-30R-0F-0G-4A-13W-16C)
Aim: To train students to critically evaluate recent peer-reviewed publications in Biotechnology.
Content: Advances in biotechnology principles and biotechnological applications.
Assessment: Test (25%), Performance in Tutorials (15%), Seminars (10%), 3 h exam (50%).
DP Requirement: Class mark of 40%, attendance at 80% of tutorials.
Offered in Semester 2.
Fermentation Microbiology
MICR720 P2 (30L-6T-0P-0S-33H-6R-0F-0G-5A-13W-8C)
Prerequisite: MICR350.
Aim: To provide the skills required in establishing and maintaining an industrial microbiological process.
Content: Screening and selection procedures for strain improvement. Scale-up; maintenance of sterility and foam control. Bioreactor design - production methods; batch, fed-batch and continuous culture processes. Immobilisation of
whole cells. Selection, preparation and pre-treatment of feedstocks. Product recovery and downstream processing and waste treatment.
Assessment: Performance in tests, tutorials, assignments & presentations (33%), 2 h exam (67%).
DP Requirement: Class mark of 40%, attendance at 80% of tutorials and practicals.
Offered in Semester 2.